The Ōshū Kaidō (奥州街道) was one of the five routes of the Edo period. It was built to connect Edo (modern-day Tokyo) with Mutsu Province and the present-day city of Shirakawa, Fukushima Prefecture, Japan. It was established by Tokugawa Ieyasu for government officials traveling through the area.

In the early Edo period, travel along the road mostly consisted of magistrates heading towards Edo in order to take part in sankin kōtai. After Hakodate's development, the late Edo period saw travel further increase as a result of increasing trade with Russia.

Nowadays, the pather of the Ōshū Kaidō is followed by National Route 4, which runs parallel to the Tōhoku Expressway and the Hachinohe Expressway. (per Wikipedia)

The 27 stations of the Ōshū Kaidō are listed below in order and are divided by their modern-day prefecture. The first seventeen stations are shared with the Nikkō Kaidō.